Search Results for Immunology
The invention consists of new bi-functional protein inhibitors (“BPIs”) for treatment and diagnostics of autoimmune diseases such as MS and experimental autoimmune encephalomyelitis. The novel BPIs are capable of modulating the immune response towards a TH2 response.
Category(s): therapeutics
Subcategory(s): biologics
Novel ligands designed to activate mu opioid receptors and provide analgesic effects without opioid-related side effects, providing specific insight into the cellular impact of opioid receptor-based activation as related to pain medications. These ligands could be used as a tool to negate drug tolerance and dependence as well as other adverse side effects.
Immuno-oncology represents the new wave of personalized medicine. Scientists at the University of Kansas have developed an innovative approach to activate intracellular signaling pathways that enhance T cell activation, expansion, and differentiation.
Category(s): biotechnology, therapeutics
Subcategory(s): biologics, healthcare
Broad-spectrum antiviral compounds that inhibits pyrimidine biosynthesis, triggers innate immunity, and induces antiviral responses.
Category(s): biotechnology, therapeutics
Subcategory(s): cell-lines, vaccines
The invention provides novel compounds (adjuvants) that can be used as agonists for Toll-Like Receptor 7 (TLR7). By specifically targeting TLR7, these adjuvants elicit a type 1 interferon response which is essential in the development of antiviral responses.
Category(s): therapeutics
The invention offers novel composition of matter to be used in treatment of a number of hormone responsive cancers.
Category(s): therapeutics
Small molecule adjuvants that act as vaccine adjuvants by specifically binding to Toll-Like Receptor-8 (TLR8).
Category(s): therapeutics
Small molecule compounds that act as vaccine adjuvants by specifically binding to Toll-Like Receptor-2 (TLR2).
Category(s): biotechnology, therapeutics
This invention provides compounds for modulating T-cell pathways and subsequent immunity.
Category(s): therapeutics
Subcategory(s): small-molecules
Conjugate compositions that combine a functionalized I-domain peptide covalently bound to multiple signal-1 blocking moieties to reduce type-1 immune responses.
Category(s): therapeutics
Subcategory(s): small-molecules