Search Results for Tumor
This invention is a tubular electrospun scaffold of natural protein gelatin and synthetic polyglycolic acid (PGA) / poly-lactic-co-glycolic (PLGA) polymers in a bioreactor system connected to a flow circuit and seeded with cultured fibroblasts and endothelial cells.
Subcategory(s): cell-lines, healthcare
Novel ligands designed to activate mu opioid receptors and provide analgesic effects without opioid-related side effects, providing specific insight into the cellular impact of opioid receptor-based activation as related to pain medications. These ligands could be used as a tool to negate drug tolerance and dependence as well as other adverse side effects.
Photo-mediated Ultrasound Therapy (PUT) is a non-pharmacological, highly targeted, non-invasive treatment which selectively disrupts the microvasculature (arteries or veins independently) without catheterization/injection or damage to the surrounding tissue.
Category(s): medical-devices, therapeutics
Subcategory(s): healthcare
Immuno-oncology represents the new wave of personalized medicine. Scientists at the University of Kansas have developed an innovative approach to activate intracellular signaling pathways that enhance T cell activation, expansion, and differentiation.
Category(s): biotechnology, therapeutics
Subcategory(s): biologics, healthcare
A novel anti-metastasis therapy for prostate cancer, utilizing the newly established small-activating RNA (saRNA) technique to up-regulate the expression of the tumor metastasis suppressor gene, dihydropyrimidase-like 3 (DPYSL3).
Category(s): therapeutics
The invention offers novel composition of matter to be used in treatment of a number of hormone responsive cancers.
Category(s): therapeutics
Novel derivatives of marmelin are anticancer agents that induce apoptosis, affect cancer stem cells, and inhibit tumor growth. Marmelin analogs have potential as chemotherapeutic agents.
Category(s): therapeutics
Subcategory(s): healthcare, stem-cells
This invention consists of a novel compound and method for treating Polycystic Kidney Disease utilizing a novel liver kinase B1 (LKB1) activator to stimulate AMP-activated protein kinase (AMPK), leading to inhibition of mTOR-mediated cellular proliferation and chloride-dependent fluid secretion, key components of cyst growth.
Category(s): therapeutics
Subcategory(s): healthcare, small-molecules
This invention is a novel composition of matter that facilitates delivery of agents (e.g. diagnostic, therapeutic, imaging, etc.) into cells
Subcategory(s): biochemicals, small-molecules
This invention utilizes a delivery system that allows for a biologically relevant moiety to be delivered to a desired cell by utilizing a transporting agent that binds two receptors expressed by that cell. This decreases the toxicity that is shown by the active compound by delivering it only to a targeted cell.
Subcategory(s): biochemicals, small-molecules