This invention consists of a novel compound and method for treating Polycystic Kidney Disease utilizing a novel liver kinase B1 (LKB1) activator to stimulate AMP-activated protein kinase (AMPK), leading to inhibition of mTOR-mediated cellular proliferation and chloride-dependent fluid secretion, key components of cyst growth.
A novel device for the treatment of vascular malformations, aneurysms, fistulas, and varices utilizing cyanoacrylate tissue adhesives. This invention provides superior control of the adhesive following injection and during the curing process, significantly decreasing the risks attributable to current technology.
A lightweight, laser-based sensor system that augments an onboard autopilot with accurate altitude and attitude measurements, enabling automated landing of uncrewed aerial vehicles (UAVs).
Development status: completed system-level simulation; exp. proof-of-concept in lab (1-Hz meas rate)