Duct Occlusion Device

Track Code: 

A novel device for the treatment of vascular malformations, aneurysms, fistulas, and varices utilizing cyanoacrylate tissue adhesives. This invention provides superior control of the adhesive following injection and during the curing process, significantly decreasing the risks attributable to current technology.


Cyanoacrylate tissue adhesives commonly used to close wounds and surgical incisions have been increasingly utilized in the treatment of a variety of vascular malformations and fistula types. These new procedures are unnecessarily difficult, however, because existing devices and adhesive compounds were not designed to provide the degree of control necessary to prevent damage to contiguous structures. The invention solves this problem, making the precise placement of cyanoacrylate plugs easier, safer and more effective.


Treatment of biliary and pancreatic duct leaks, arteriovenous malformations, vascular aneurysms, gastric varices and fistulas.

How it works: 

In these applications, cyanoacrylate must be delivered with precision to the desired location and maintained in position while polymerization occurs. The invention utilizes novel cyanoacrylate adhesives with unique features in conjunction with a catheter designed to hold the adhesive in place near the catheter tip following injection and throughout the curing process. This results in unprecedented control of the adhesive, even in open-ended ducts.


The lack of adhesive control has resulted in limited use of cyanoacrylates for the purposes of aneurysm and fistula closure. By maintaining the adhesive in a given position, the risk of obstructing contiguous structures due to imprecise placement can be significantly reduced, as is the risk of adhesive embolization when used intravascularly. The device also prevents dislodgement of newly formed adhesive plug during catheter removal.

Why it is better: 

This invention gives practitioners fine control of adhesives outside the delivery catheter following injection and during the curing process, eliminating risks associated with existing technology and making procedures safer and more effective.

Other Applications: 

The invention is suitable for many other tissue types and organ systems, beyond those mentioned above.

Licensing Associate: 
Aswini Betha, PhD · abetha@ku.edu · 913-588-5713
Stephen Waller
Sarah Seguin
Richard Gilroy
Philip Johnson