The invention provides novel compounds (adjuvants) that can be used as agonists for Toll-Like Receptor 7 (TLR7). By specifically targeting TLR7, these adjuvants elicit a type 1 interferon response which is essential in the development of antiviral responses.
The current invention is a novel class of compounds that function as KOR antagonists. Because KOR activation has been linked to depression and anxiety related disorders, this novel class of compounds may be used in the development of therapies to treat these mental disorders
The current invention is a method for using inexpensive and widely available silica nanoparticles as a fluid loss prevention agent and nanoproppant to maintain micro-fractures during hydraulic fracturing (fracking) to extract oil or natural gas from a variety of geological formations.
This invention consists of a new hyphenated atomic force microscopy (AFM) technique with whispering gallery mode sensing (WGM), which provides the ability to measure the topography and refractive index of a material simultaneously.