A mechanical barrier system for reducing infections associated with intravascular catheters. The invention reduces the risk of bacterial contamination of the outer surface of the catheter at the skin entry site, which in turn prevents more serious infections caused by the spread of bacteria down the surface of the catheter into the bloodstream. The barrier device functions by forming an occlusive "boot" at the skin exit site and relies on use of a cyanoacrylate adhesive to complete the occlusive junction between the boot and the contaminated skin. At time of device removal, the device-adhesive bond is safely broken through a novel bladder release method, allowing for safe removal of the vascular catheter.
Based on precision drug delivery technologies, ConocoPhilips and KU have jointly developed a patented technology using polyelectrolyte complex (PEC) nanoparticles to entrap/protect and delay the release of oil and gas field chemicals.
This innovation has two forms: a hard capsule that dissolves orally and a film that dissolves orally. The capsules can be filled with a drug formulation containing an active drug or drugs, excipients, and flavors.