Transmission of blood-borne infections (e.g., HIV) from health care exposures was previously believed to be uncommon. However, multiple outbreaks across the U.S. over the last several years have shed light on this problem. Thousands of individuals exposed to potential blood-borne pathogens. As recently as October 2009, in one of the hospitals in Florida, the nurse routinely used the same bag of saline on multiple patients. In another outbreak in an outpatient oncology clinic in Nebraska, the nurse would reuse a syringe to perform a saline flush. Saline for multiple patients was acquired from a common bag. More than 600 patients were notified and 99 patients were diagnosed with Hepatitis C. These cases all have in common acquisition of saline or a drug from a common container via a contaminated needle and/or syringe. Despite the increasing use of single-dose vials, such outbreaks occur as providers still use these single-dose vials on multiple individuals to reduce costs.