Search Technologies

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Summary:
This invention utilizes a delivery system that allows for a biologically relevant moiety to be delivered to a desired cell by utilizing a transporting agent that binds two receptors expressed by that cell. This decreases the toxicity that is shown by the active compound by delivering it only to a targeted cell.
Subcategory(s): biochemicals, small-molecules
Inventor(s): Blake Peterson, Matthew Levy, Liang Xu


Summary:
The invention provides a "sample-in-answer-out" microfluidic exosome profiling platform which integrates immunoaffinity isolation of plasma exosomes with quantitative detection of both surface and intravesicular markers for characterization of exosomal phenotypes.
Subcategory(s): assays, biomarkers, purification
Inventor(s): Andrew Godwin, Yong Zeng, Mei He


Summary:
The present invention employs a novel use of logic and data analysis tools to improve the efficiency of drug discovery.
Subcategory(s): drug-screening
Keyword(s): bioinformatics
Inventor(s): Swapan Chakrabarti, Arunabha Choudhury, Ghaith Shabsigh


Summary:
This invention is a novel composition of matter that disrupts endosomes allowing for the release of biologically active agents into the cytosol.
Subcategory(s): biochemicals, small-molecules
Inventor(s): Blake Peterson


Summary:
KU researchers have developed a novel apparatus and associated method for the in situ formation of multi-layer thin film structures using atomic layer deposition (ALD) and ultra-high vacuum (UHV) physical/chemical vapor deposition.
Subcategory(s): energy-storage, sensors
Keyword(s): film, nano, semiconductor
Inventor(s): Judy Wu, Allen Hase, Alan Elliot, Rongtao Lu


Summary:
In contrast to conventional ethylene oxide (EO) production methods, this invention employs a new catalyst, a different oxidant, and much milder operating conditions. This inventive method eliminates carbon dioxide waste and converts ethylene to EO with greater than 99% selectivity. In addition to increased efficiency and a reduced carbon footprint, this invention offers safety advantages over conventional methods. The current inventions utilizes a novel metal based catalyst in order to allow for the use of hydrogen peroxide as an oxidant allowing for a greener approach to olefin epoxidation. Further this method employs a catalyst that allows for less metal leaching, decreases hydrogen peroxide decomposition, and no carbon dioxide byproduct as demonstrated by gas chromatography.
Keyword(s): crude, petroleum
Inventor(s): Bala Subramaniam, Anand Ramanathan, Madhav Ghanta


Summary:
This invention consists of a novel composition of matter as well as a process for the efficient conversion of glycerol to lactic acid.
Inventor(s): Bala Subramaniam, Debdut Roy, Raghunath Chaudhari


Summary:
The invention offers high load reagents and scavengers which combine the physical properties of the silica surface with the inherent tunable properties of the ROMP-derived oligomers.
Keyword(s): nano
Inventor(s): Paul Hanson, Alan Rolfe


Summary:
This invention is a process to convert a biomass side product, glycerol, into an industrial chemical. The process eliminates the previous step of externally adding hydrogen to create a more efficient product with a higher yield of product with lower deoxygenation.
Keyword(s): crude, petroleum
Inventor(s): Bala Subramaniam, Debdut Roy, Raghunath Chaudhari


Summary:
This invention is a novel catalyst made up of a support, a linker, and a ruthenium catalyst nanoparticle. The invention covers not only synthesis of the catalyst but also methods of performing hydrogenolysis with the catalyst.
Keyword(s): crude, petroleum
Inventor(s): Bala Subramaniam, Debdut Roy, Raghunath Chaudhari

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