This invention entails a novel, nonhormonal compound that can sterilize both male and female companion animals in a single dose.
Surgical sterilization of companion animals is the most common procedure performed by veterinarians. However, a high number of unwanted pets and related rates of euthanasia still occur. Current non-surgical alternatives to sterilization are unsuitable for use in a field setting due to their lack of cross-gender effect, poor efficacy and toxic side effects.
Proof of concept has been shown in mice, rats and rabbits. The compound is not positive in hERG assays, non-mutagenic, and exhibits 100% bioavailability and desirable pharmacokinetics for use as a single dose sterilant.
A safe, permanent, easily administered single dose sterilant for use in both male and female animals will reduce the large number of unwanted pets and the burden to pet owners, animal control, and veterinary facilities.